Blar i forfatter "Kringen, Marianne K."
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E.S. Dietrichs og medarbeidere svarer
Dietrichs, Erik Sveberg; Solhaug, Vigdis; Haslemo, Tore; Kringen, Marianne K.; Molden, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-21) -
Impact of liver fibrosis and clinical characteristics on dose-adjusted serum methadone concentrations
Chalabianloo, Fatemeh; Høiseth, Gudrun; Vold, Jørn Henrik; Johansson, Kjell Arne; Kringen, Marianne K.; Dalgard, Olav; Ohldieck, Christian; Druckrey-Fiskaaen, Karl Trygve; Aas, Christer Frode; Løberg, Else-Marie; Bramness, Jørgen Gustav; Fadnes, Lars T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)Background: There is limited knowledge on the causes of large variations in serum methadone concentrations and dose requirements. Objectives: We investigated the impact of the degree of liver fibrosis on dose-adjusted steady-state serum methadone concentrations.<p> <p<Methods: We assessed the clinical and laboratory data of 155 Norwegian patients with opioid use disorder undergoing methadone ... -
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications
Chalabianloo, Fatemeh; Fadnes, Lars T.; Johansson, Kjell Arne; Høiseth, Gudrun; Vold, Jørn Henrik; Kringen, Marianne K.; Spigset, Olav; Bramness, Jørgen Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-20)Background: A considerable inter-individual variability has been reported in the relationship between methadone doses applied and serum concentrations achieved in methadone maintenance treatment. However, the underlying causes for this variability are not fully understood.<p> <p>Objectives: We investigated the influence of genetic, pathophysiological and pharmacological factors on serum methadone ...